Dr. Iruka Okeke, Haverford College
Friday, November 9, 2012 at 1:10pm
Thompson Biology, 112 59 Lab Campus Dr, Williamstown, MA 01267
Enteroaggregative Escherichia coli are a category of diarrhea-causing E. coli defined by their characteristic stacked-brick pattern of adherence. Our laboratory uses EAEC strains as models for exceptional colonization. The EAEC strains we study express aggregative adherence fimbrae, outer surface agglutinins and an anti-aggregative factor. These three factors have, as is traditional, been studied separately. We find that optimal colonization by EAEC is produced by the interplay among these and potentially other factors.
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